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Psychedelic Information Theory

Shamanism in the Age of Reason

Search Results : "pyramidal neurons"

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5-HT2A Agonism and Multisensory Binding

Most visual hallucinogens are active as full or partial agonists at the 5-HT2A receptor subtype, and all produce similar visual hallucinations that are immediately recognizable as psychedelic.1 Although the 5-HT2A receptor subtype is not the only rec...

Entoptic Hallucination

... flooding at lateral dendritic arbors of pyramidal neurons is the result of asynchronous glutamate release in the wake of 5-HT2A receptor agonism.19 [fig]7;1[/fig]It is widely assumed that geometric hallucinations and flicker phosphenes o...

The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain

... 5-HT1A receptor mRNA to be concentrated in pyramidal neurons, together with the granule cells of the dentate gyrus. In neocortical areas lamina III pyramidal neurons were more heavily labelled than those in lamina V. There was no evidence of g...

How Hallucinogens Play Their Mind-Bending Games

... localized the effects of hallucinogens to the pyramidal neurons in layer V of the somatosensory cortex, a relatively high-level region known to modulate the activity of other sections in the cortex and subcortical areas. Using what he calls an "i...

5-Hydroxytryptamine2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

... The majority of the receptor-labeled cells were pyramidal neurons and the most intense immunolabeling was consistently confined to their parallelly aligned proximal apical dendrites that formed two intensely stained bands above and below layer IV. ...

Presynaptic regulation of recurrent excitation by D1 receptors in prefrontal circuits

... is thought to involve recurrent excitation among pyramidal neurons. Recent studies in awake behaving monkeys have demonstrated that the persistent activity in prefrontal neurons is modulated by dopamine. To examine the mechanisms by which dopamine m...

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